Grin1 (NM_008169) Mouse Recombinant Protein

Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg (2+) (PubMed:1532151, PubMed:8060614, PubMed:12008020) . Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:12008020) .[UniProtKB/Swiss-Prot Function]

Purified recombinant protein of Mouse glutamate receptor, ionotropic, NMDA1 (zeta 1) (Grin1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.