Cry1 (NM_007771) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by Clock/Arntl heterodimers but then represses this upregulation in a feedback loop using Per/Cry heterodimers to interact with Clock/Arntl. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of this gene results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Feb 2014]
Synonyms
AU020726; AU021000; Phll1
Gene ID
12952
UniProt
P97784
Accession Number mRNA
NM_007771
Chromosomal Location
10 41.63 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
68.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cry1
Species
Mouse
Protein ID
NP_031797
Overview
Purified recombinant protein of Mouse cryptochrome 1 (photolyase-like) (Cry1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12952
Uniprot URL
https://www.uniprot.org/uniprot/P97784
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007771
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031797
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