Runx1t1 (NM_001111026) Mouse Recombinant Protein
Selected Variant
PM42711M5
Size: 20 µg
Product Specifications
Background
Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Can repress the expression of MMP7 in a ZBTB33-dependent manner. Can repress transactivation mediated by TCF12 (By similarity) . Acts as a negative regulator of adipogenesis (PubMed:23527555) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse RUNX1 translocation partner 1 (Runx1t1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Cbfa2t1h; ETO; MTG8
Gene ID
12395
UniProt
Q3UQX8, Q8C066
Accession Number mRNA
NM_001111026
Chromosomal Location
4 5.88 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
65.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Runx1t1
Species
Mouse
Protein ID
NP_001104496
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12395
Uniprot URL
https://www.uniprot.org/uniprot/Q3UQX8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001111026
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001104496
Price
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