Cdk6 (NM_009873) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes a member of the cyclin dependent kinase family of proteins that play important roles in the progression and regulation of the cell cycle. The encoded protein binds to a D-type cyclin to form an active kinase complex to regulate progression through the G1 phase of the cell cycle. Mice lacking the encoded protein exhibit thymic and splenic hypoplasia, and hematopoietic defects such as reduced number of megakaryocytes and erythrocytes. A pseudogene of this gene has been defined on chromosome 4. [provided by RefSeq, Aug 2015]
Synonyms
AI504062; Crk; Crk2
Gene ID
12571
UniProt
Q64261, Q0VBK8
Accession Number mRNA
NM_009873
Chromosomal Location
5 2.04 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
37.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cdk6
Species
Mouse
Protein ID
NP_034003
Overview
Purified recombinant protein of Mouse cyclin-dependent kinase 6 (Cdk6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12571
Uniprot URL
https://www.uniprot.org/uniprot/Q64261
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009873
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034003
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