Btla (NM_001037719) Mouse Recombinant Protein
Product Specifications
Background
Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006) . May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044) . In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed:19915044) .[UniProtKB/Swiss-Prot Function]
Synonyms
A630002H24
Gene ID
208154
UniProt
Q7TSA3, E9QNY6, Q32MV8
Accession Number mRNA
NM_001037719
Chromosomal Location
16 B5
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
34.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Btla
Species
Mouse
Protein ID
NP_001032808
Overview
Purified recombinant protein of Mouse B and T lymphocyte associated (Btla), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/208154
Uniprot URL
https://www.uniprot.org/uniprot/Q7TSA3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001037719
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001032808
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