Cplx2 (NM_009946) Mouse Recombinant Protein
Product Specifications
Background
Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles (PubMed:11163241, PubMed:23345244) . Also involved in mast cell exocytosis (PubMed:11163241) . Although not essential for development, seems critical for the acquisition of higher cognitive functions in the adult brain (PubMed:12915444) .[UniProtKB/Swiss-Prot Function]
Synonyms
921-L; AI413745; AW492120
Gene ID
12890
UniProt
P84086
Accession Number mRNA
NM_009946
Chromosomal Location
13 B1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
15.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Cplx2
Species
Mouse
Protein ID
NP_034076
Overview
Purified recombinant protein of Mouse complexin 2 (Cplx2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12890
Uniprot URL
https://www.uniprot.org/uniprot/P84086
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009946
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034076
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