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Scn4b (NM_001013390) Mouse Recombinant Protein

Product Specifications

Background

Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse sodium channel, type IV, beta (Scn4b), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Gm1471

Gene ID

399548

UniProt

Q7M729, Q1MXF9

Accession Number mRNA

NM_001013390

Chromosomal Location

9 A5.2

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

25.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Scn4b

Species

Mouse

Protein ID

NP_001013408

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/399548

Uniprot URL

https://www.uniprot.org/uniprot/Q7M729

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001013390

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001013408

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