Msh5 (NM_001146215) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes a member of the MutS family of proteins that play critical roles in DNA mismatch repair and meiotic homologous recombination processes. Mice lacking the encoded protein are viable but sterile, with severe defects in spermatogenesis in males and complete loss of ovarian structures in females. Mutations in a similar gene in humans have been shown to cause common variable immune deficiency (CVID) and immunoglobulin A deficiency. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Synonyms
Mut5
Gene ID
17687
UniProt
Q9QUM7, A0A0R4IZY8
Accession Number mRNA
NM_001146215
Chromosomal Location
17 18.57 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
92.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Msh5
Species
Mouse
Protein ID
NP_001139687
Overview
Purified recombinant protein of Mouse mutS homolog 5 (Msh5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/17687
Uniprot URL
https://www.uniprot.org/uniprot/Q9QUM7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001146215
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001139687
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
