Ptpra (NM_008980) Mouse Recombinant Protein

Product Specifications

Background

Tyrosine protein phosphatase which is involved in integrin-mediated focal adhesion formation (PubMed:22801373) . Following integrin engagement, specifically recruits BCAR3, BCAR1 and CRK to focal adhesions thereby promoting SRC-mediated phosphorylation of BRAC1 and the subsequent activation of PAK and small GTPase RAC1 and CDC42 (PubMed:22801373) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse protein tyrosine phosphatase, receptor type, A (Ptpra), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Ptpa; Ptpalpha; Rptpalpha; Rptra; Rptralpha

Gene ID

19262

UniProt

P18052, Q91V35, Q3TRY9

Accession Number mRNA

NM_008980

Chromosomal Location

2 63.23 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

94.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.