Trim6 (NM_001013616) Mouse Recombinant Protein
Selected Variant
PM42629M5
Size: 20 µg
Product Specifications
Background
E3 ubiquitin-protein ligase which ubiquitinates MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells (PubMed:22328504) . Involved in the synthesis of unanchored K48-linked polyubiquitin chains which interact with and activate the serine/threonine kinase IKBKE, leading to phosphorylation of STAT1 and stimulation of an antiviral response (PubMed:24882218) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse tripartite motif-containing 6 (Trim6), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
C430046K18Rik; D7Ertd684e
Gene ID
94088
UniProt
Q8BGE7
Accession Number mRNA
NM_001013616
Chromosomal Location
7 55.55 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
56.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Trim6
Species
Mouse
Protein ID
NP_001013637
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/94088
Uniprot URL
https://www.uniprot.org/uniprot/Q8BGE7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001013616
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001013637
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