Tnc (NM_011607) Mouse Recombinant Protein
Product Specifications
Background
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth when provided to neurons in culture. May play a role in supporting the growth of epithelial tumors. Ligand for integrins ITGA8:ITGB1, ITGA9:ITGB1, ITGAV:ITGB3 and ITGAV:ITGB6. In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
AI528729; C130033P17Rik; cytotactin; Hxb; Ten; tenascin-C; TN; TN-C
Gene ID
21923
UniProt
Q80YX1, Q148T5, Q8C9Z1
Accession Number mRNA
NM_011607
Chromosomal Location
4 34.06 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
222.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Tnc
Species
Mouse
Protein ID
NP_035737
Overview
Purified recombinant protein of Mouse tenascin C (Tnc), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/21923
Uniprot URL
https://www.uniprot.org/uniprot/Q80YX1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_011607
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_035737
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