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Dok3 (NM_013739) Mouse Recombinant Protein

Product Specifications

Background

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse docking protein 3 (Dok3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AI450713; Dokl

Gene ID

27261

UniProt

Q9QZK7, Q14AA1

Accession Number mRNA

NM_013739

Chromosomal Location

13 B1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

48 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Dok3

Species

Mouse

Protein ID

NP_038767

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/27261

Uniprot URL

https://www.uniprot.org/uniprot/Q9QZK7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_013739

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_038767

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