Dok3 (NM_013739) Mouse Recombinant Protein
Product Specifications
Background
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function.[UniProtKB/Swiss-Prot Function]
Synonyms
AI450713; Dokl
Gene ID
27261
UniProt
Q9QZK7, Q14AA1
Accession Number mRNA
NM_013739
Chromosomal Location
13 B1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
48 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Dok3
Species
Mouse
Protein ID
NP_038767
Overview
Purified recombinant protein of Mouse docking protein 3 (Dok3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/27261
Uniprot URL
https://www.uniprot.org/uniprot/Q9QZK7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013739
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_038767
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