Ins2 (NM_001185083) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. The encoded precursor protein undergoes proteolytic cleavage to produce a disulfide-linked heterodimeric functional protein that is stored in secretory granules. An increase in blood glucose levels, among others, induces the release of insulin from the secretory granules. Mice deficient in the functional hormone encoded by this gene develop diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Synonyms
AA986540; In; Ins-2; InsII; Mod; Mody; Mody4
Gene ID
16334
UniProt
P01326, Q5EEX1
Accession Number mRNA
NM_001185083
Chromosomal Location
7 88.0 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
12.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Ins2
Species
Mouse
Protein ID
NP_001172012
Overview
Purified recombinant protein of Mouse insulin II (Ins2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/16334
Uniprot URL
https://www.uniprot.org/uniprot/P01326
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001185083
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001172012
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