Mmp9 (NM_013599) Mouse Recombinant Protein
Product Specifications
Background
This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme that degrades collagens of type IV, V and XI, and elastin. Mice lacking the encoded protein exhibit an abnormal pattern of skeletal growth plate vascularization and ossification, reduced keratinocyte hyperproliferation at all neoplastic stages, a decreased incidence of invasive tumors, and resistance to experimental autoimmune encephalomyelitis. [provided by RefSeq, Feb 2016]
Synonyms
AW743869; B/MMP; B/MMP9; Clg4; Clg4b; Gel B; MMP-; MMP-9; pro-MMP-9
Gene ID
17395
UniProt
P41245
Accession Number mRNA
NM_013599
Chromosomal Location
2 85.27 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
81 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Mmp9
Species
Mouse
Protein ID
NP_038627
Overview
Purified recombinant protein of Mouse matrix metallopeptidase 9 (Mmp9), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/17395
Uniprot URL
https://www.uniprot.org/uniprot/P41245
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013599
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_038627
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