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Rasgrp2 (NM_011242) Mouse Recombinant Protein

Product Specifications

Background

Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse RAS, guanyl releasing protein 2 (Rasgrp2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Caldaggef1; CDC25L

Gene ID

19395

UniProt

Q9QUG9

Accession Number mRNA

NM_011242

Chromosomal Location

19 A

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

69.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Rasgrp2

Species

Mouse

Protein ID

NP_035372

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/19395

Uniprot URL

https://www.uniprot.org/uniprot/Q9QUG9

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_011242

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_035372

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