Rasgrp2 (NM_011242) Mouse Recombinant Protein
Product Specifications
Background
Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May also activates other GTPases such as RRAS, RRAS2, NRAS, KRAS but not HRAS. Functions in aggregation of platelets and adhesion of T-lymphocytes and neutrophils probably through inside-out integrin activation. May function in the muscarinic acetylcholine receptor M1/CHRM1 signaling pathway.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse RAS, guanyl releasing protein 2 (Rasgrp2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
Caldaggef1; CDC25L
Gene ID
19395
UniProt
Q9QUG9
Accession Number mRNA
NM_011242
Chromosomal Location
19 A
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
69.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Rasgrp2
Species
Mouse
Protein ID
NP_035372
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/19395
Uniprot URL
https://www.uniprot.org/uniprot/Q9QUG9
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_011242
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_035372
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