Smad1 (NM_008539) Mouse Recombinant Protein
Product Specifications
Background
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) (By similarity) . May play a role in the initiation and maintenance of spermatogenesis. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1 (By similarity) . May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP) -mediated cardiac-specific gene expression (PubMed:15329343) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse SMAD family member 1 (Smad1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
AI528653; Madh1; Madr1; Mlp1; MusMLP
Gene ID
17125
UniProt
P70340
Accession Number mRNA
NM_008539
Chromosomal Location
8 C1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
52.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Smad1
Species
Mouse
Protein ID
NP_032565
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/17125
Uniprot URL
https://www.uniprot.org/uniprot/P70340
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_008539
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_032565
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