Smad1 (NM_008539) Mouse Recombinant Protein

Product Specifications

Background

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) (By similarity) . May play a role in the initiation and maintenance of spermatogenesis. SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1 (By similarity) . May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP) -mediated cardiac-specific gene expression (PubMed:15329343) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse SMAD family member 1 (Smad1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AI528653; Madh1; Madr1; Mlp1; MusMLP

Gene ID

17125

UniProt

P70340

Accession Number mRNA

NM_008539

Chromosomal Location

8 C1

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

52.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.