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Sfn (NM_018754) Mouse Recombinant Protein

Selected Variant

PM42480M5

Size: 20 µg

Product Specifications

Background

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse stratifin (Sfn), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

Er; Mme1; Ywhas

Gene ID

55948

UniProt

O70456

Accession Number mRNA

NM_018754

Chromosomal Location

4 66.25 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

28.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Sfn

Species

Mouse

Protein ID

NP_061224

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/55948

Uniprot URL

https://www.uniprot.org/uniprot/O70456

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_018754

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_061224

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