Nck2 (NM_010879) Mouse Recombinant Protein
Product Specifications
Background
Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1. Plays a role in ELK1-dependent transcriptional activation in response to activated Ras signaling (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
4833426I10Rik; Grb4; Nck-2; NCKbeta
Gene ID
17974
UniProt
O55033, Q8BQ28
Accession Number mRNA
NM_010879
Chromosomal Location
1 C1.1
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
42.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Nck2
Species
Mouse
Protein ID
NP_035009
Overview
Purified recombinant protein of Mouse non-catalytic region of tyrosine kinase adaptor protein 2 (Nck2), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/17974
Uniprot URL
https://www.uniprot.org/uniprot/O55033
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010879
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_035009
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