Fkbp4 (NM_010219) Mouse Recombinant Protein
Product Specifications
Background
Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) . May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.[UniProtKB/Swiss-Prot Function]
Synonyms
59kDa; AL022792; AW208983; FKBP-4; FKBP-52; FKBP52; FKPB52; p59
Gene ID
14228
UniProt
P30416
Accession Number mRNA
NM_010219
Chromosomal Location
6 F3
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
52 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Fkbp4
Species
Mouse
Protein ID
NP_034349
Overview
Purified recombinant protein of Mouse FK506 binding protein 4 (Fkbp4), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/14228
Uniprot URL
https://www.uniprot.org/uniprot/P30416
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010219
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034349
Curated Selection
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