Kcnj6 (NM_010606) Mouse Recombinant Protein
Product Specifications
Background
This potassium channel is controlled by G proteins. It plays a role in granule cell differentiation, possibly via membrane hyperpolarization. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.[UniProtKB/Swiss-Prot Function]
Synonyms
BIR1; GIRK2; KATP2; KCNJ7; Kir3.2; weaver; wv
Gene ID
16522
UniProt
P48542, Q0VB45, Q8C8Y6
Accession Number mRNA
NM_010606
Chromosomal Location
16 55.44 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
49.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Kcnj6
Species
Mouse
Protein ID
NP_034736
Overview
Purified recombinant protein of Mouse potassium inwardly-rectifying channel, subfamily J, member 6 (Kcnj6), transcript variant Girk2A-1, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/16522
Uniprot URL
https://www.uniprot.org/uniprot/P48542
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010606
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034736
Curated Selection
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