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Kcnj6 (NM_010606) Mouse Recombinant Protein

Product Specifications

Background

This potassium channel is controlled by G proteins. It plays a role in granule cell differentiation, possibly via membrane hyperpolarization. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse potassium inwardly-rectifying channel, subfamily J, member 6 (Kcnj6), transcript variant Girk2A-1, with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

BIR1; GIRK2; KATP2; KCNJ7; Kir3.2; weaver; wv

Gene ID

16522

UniProt

P48542, Q0VB45, Q8C8Y6

Accession Number mRNA

NM_010606

Chromosomal Location

16 55.44 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

49.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Kcnj6

Species

Mouse

Protein ID

NP_034736

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/16522

Uniprot URL

https://www.uniprot.org/uniprot/P48542

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_010606

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_034736

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