Cdh3 (NM_007665) Mouse Recombinant Protein

Product Specifications

Background

This gene encodes a calcium-dependent cell-cell adhesion protein containing five cadherin domains. The encoded protein plays a role in epithelial outgrowth, such as that which occurs during the development of hair follicles and limb buds. Loss of function of the related gene in humans results in ectodermal dysplasia, ectrodactyly, and macular dystrophy and congential hypotrichosis with juvenile macular dystrophy. This gene is located in the vicinity of similar cadherin genes on chromosome 8. The proprotein is further cleaved into a functional chain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Overview

Purified recombinant protein of Mouse cadherin 3 (Cdh3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

AI385538; Ca; Cadp; Cdhp; P-cad; P-cadherin; Pc; Pcad

Gene ID

12560

UniProt

Q8BRE1

Accession Number mRNA

NM_007665

Chromosomal Location

8 53.16 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

91 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.