Slc6a4 (NM_010484) Mouse Recombinant Protein
Product Specifications
Background
Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 (Slc6a4), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
5-HTT; AI323329; Htt; Sert
Gene ID
15567
UniProt
Q60857
Accession Number mRNA
NM_010484
Chromosomal Location
11 46.18 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
70.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Slc6a4
Species
Mouse
Protein ID
NP_034614
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/15567
Uniprot URL
https://www.uniprot.org/uniprot/Q60857
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_010484
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_034614
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