Bbc3 (NM_133234) Mouse Recombinant Protein
Product Specifications
Background
Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53 (By similarity) . Regulates ER stress-induced neuronal apoptosis.[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse BCL2 binding component 3 (Bbc3), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
PUMA; PUMA/JFY1
Gene ID
170770
UniProt
Q99ML1, B2RVL4
Accession Number mRNA
NM_133234
Chromosomal Location
7 A2
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
21.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Bbc3
Species
Mouse
Protein ID
NP_573497
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/170770
Uniprot URL
https://www.uniprot.org/uniprot/Q99ML1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_133234
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_573497
Curated Selection
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