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Adipoq (NM_009605) Mouse Recombinant Protein

Product Specifications

Background

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of Mouse adiponectin, C1Q and collagen domain containing (Adipoq), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

Synonyms

30kDa; Acdc; Acrp30; Ad; adipo; apM1; APN; GBP28

Gene ID

11450

UniProt

Q60994

Accession Number mRNA

NM_009605

Chromosomal Location

16 13.96 cM

Expression System

HEK293T

Tag

C-MYC/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Molecular Weight

27.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

Adipoq

Species

Mouse

Protein ID

NP_033735

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/11450

Uniprot URL

https://www.uniprot.org/uniprot/Q60994

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_009605

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_033735

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