Bmpr1a (NM_009758) Mouse Recombinant Protein
Selected Variant
PM42338M5
Size: 20 µg
Product Specifications
Background
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction (PubMed:24098149) . Mediates induction of adipogenesis by GDF6 (PubMed:23527555) .[UniProtKB/Swiss-Prot Function]
Overview
Purified recombinant protein of Mouse bone morphogenetic protein receptor, type 1A (Bmpr1a), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug
Synonyms
1110037I22Rik; ALK3; AU045487; Bmpr; BMPR-IA
Gene ID
12166
UniProt
P36895, Q53Z43
Accession Number mRNA
NM_009758
Chromosomal Location
14 20.81 cM
Expression System
HEK293T
Tag
C-MYC/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Weight
60.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
Bmpr1a
Species
Mouse
Protein ID
NP_033888
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/12166
Uniprot URL
https://www.uniprot.org/uniprot/P36895
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_009758
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_033888
Price
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