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PARK7 (NM_007262) Human Recombinant Protein

Product Specifications

Background

The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1

Synonyms

DJ-1; DJ1; GATD2; HEL-S-67p

Gene ID

11315

UniProt

Q99497, V9HWC2

Accession Number mRNA

NM_007262

Chromosomal Location

1p36.23

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Parkinson's disease

Field of Research

Parkinson's disease

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protease

Molecular Weight

19.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PARK7

Species

Human

Protein ID

NP_009193

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/11315

Uniprot URL

https://www.uniprot.org/uniprot/Q99497

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_007262

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_009193

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