PARK7 (NM_007262) Human Recombinant Protein
Product Specifications
Background
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human Parkinson disease (autosomal recessive, early onset) 7 (PARK7), transcript variant 1
Synonyms
DJ-1; DJ1; GATD2; HEL-S-67p
Gene ID
11315
UniProt
Q99497, V9HWC2
Accession Number mRNA
NM_007262
Chromosomal Location
1p36.23
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Parkinson's disease
Field of Research
Parkinson's disease
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protease
Molecular Weight
19.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PARK7
Species
Human
Protein ID
NP_009193
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11315
Uniprot URL
https://www.uniprot.org/uniprot/Q99497
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007262
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_009193
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