BAFF (TNFSF13B) (NM_006573) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFFR. This cytokine is expressed in B cell lineage cells, and acts as a potent B cell activator. It has been also shown to play an important role in the proliferation and differentiation of B cells. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
Overview
Recombinant protein of human tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B), transcript variant 1, secreted soluble form with N-terminal His tag, expressed in human cells
Synonyms
BAFF; BLYS; CD257; DTL; TALL-1; TALL1; THANK; TNFSF20; TNLG7A; ZTNF4
Gene ID
10673
UniProt
Q9Y275, A0A0U5J7Q1
Accession Number mRNA
NM_006573
Chromosomal Location
13q33.3
Expression System
HEK293
Tag
N-DDK/His
Related Pathways
Cytokine-cytokine receptor interaction
Field of Research
Cytokine-cytokine receptor interaction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
PBS, pH7.4, 10% glycerol
Function
Druggable Genome, Secreted Protein, Transmembrane
Molecular Weight
19 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TNFSF13B
Species
Human
Protein ID
NP_006564
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10673
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y275
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006573
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006564
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