What sizes are available for Insulin Receptor (INSR) (NM_000208) Human Recombinant Protein?

Insulin Receptor (INSR) (NM_000208) Human Recombinant Protein is available in the following size(s): 20 µg.

Insulin Receptor (INSR) (NM_000208) Human Recombinant Protein

Q: What is the catalog number for Insulin Receptor (INSR) (NM_000208) Human Recombinant Protein?

The catalog number for Insulin Receptor (INSR) (NM_000208) Human Recombinant Protein is PH32961M2.

Product Specifications

Background

This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Overview

Purified recombinant protein of Human insulin receptor, transcript variant 1, with C-terminal DDK/His tag, expressed in human cells

Synonyms

CD220; HHF5

Gene ID

3643

UniProt

P06213

Accession Number mRNA

NM_000208

Chromosomal Location

19p13.2

Expression System

HEK293

Tag

C-DDK/His

Related Pathways

Adherens junction, Insulin signaling pathway, Type II diabetes mellitus

Field of Research

Adherens junction, Insulin signaling pathway, Type II diabetes mellitus

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

PBS, pH7.4, 10% glycerol

Function

Druggable Genome, Protein Kinase, Transmembrane

Molecular Weight

25 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.