Eph receptor B1 (EPHB1) (NM_004441) Human Recombinant Protein
Product Specifications
Background
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. [provided by RefSeq, Jul 2008]
Synonyms
ELK; EPHT2; Hek6; NET
Gene ID
2047
UniProt
P54762
Accession Number mRNA
NM_004441
Chromosomal Location
3q22.2
Expression System
HEK293
Tag
C-DDK/His
Related Pathways
Axon guidance
Field of Research
Axon guidance
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
PBS, pH7.4, 10% glycerol
Function
Druggable Genome, Protein Kinase, Transmembrane
Molecular Weight
61 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EPHB1
Species
Human
Protein ID
NP_004432
Overview
Purified recombinant protein of human EPH receptor B1 (EPHB1), with C-terminal DDK/His tag, expressed in human cells, 20 µg
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2047
Uniprot URL
https://www.uniprot.org/uniprot/P54762
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004441
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004432
Curated Selection
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