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Eph receptor B1 (EPHB1) (NM_004441) Human Recombinant Protein

Product Specifications

Background

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of human EPH receptor B1 (EPHB1), with C-terminal DDK/His tag, expressed in human cells, 20 µg

Synonyms

ELK; EPHT2; Hek6; NET

Gene ID

2047

UniProt

P54762

Accession Number mRNA

NM_004441

Chromosomal Location

3q22.2

Expression System

HEK293

Tag

C-DDK/His

Related Pathways

Axon guidance

Field of Research

Axon guidance

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

PBS, pH7.4, 10% glycerol

Function

Druggable Genome, Protein Kinase, Transmembrane

Molecular Weight

61 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EPHB1

Species

Human

Protein ID

NP_004432

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2047

Uniprot URL

https://www.uniprot.org/uniprot/P54762

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004441

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004432

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