PODXL (NM_005397) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. [provided by RefSeq, Jul 2008]
Synonyms
Gp135; Gp200; PC; PCLP; PCLP-1; PDX; PODXL1
Gene ID
5420
UniProt
O00592, Q96N83
Accession Number mRNA
NM_005397
Chromosomal Location
7q32.3
Expression System
HEK293
Tag
C-DDK/His
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
PBS, pH7.4, 10% glycerol
Function
Transmembrane
Molecular Weight
44 kda
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PODXL
Species
Human
Protein ID
NP_005388
Overview
Purified recombinant protein of Homo sapiens podocalyxin-like (PODXL), transcript variant 2, residues Ser23-Pro461, expressed in HEK293 cells.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5420
Uniprot URL
https://www.uniprot.org/uniprot/O00592
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005397
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005388
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