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PODXL (NM_005397) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Homo sapiens podocalyxin-like (PODXL), transcript variant 2, residues Ser23-Pro461, expressed in HEK293 cells.

Synonyms

Gp135; Gp200; PC; PCLP; PCLP-1; PDX; PODXL1

Gene ID

5420

UniProt

O00592, Q96N83

Accession Number mRNA

NM_005397

Chromosomal Location

7q32.3

Expression System

HEK293

Tag

C-DDK/His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

PBS, pH7.4, 10% glycerol

Function

Transmembrane

Molecular Weight

44 kda

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PODXL

Species

Human

Protein ID

NP_005388

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5420

Uniprot URL

https://www.uniprot.org/uniprot/O00592

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005397

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005388

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