LGR5 (NM_003667) Human Recombinant Protein
Selected Variant
PH32901M4
Size: 20 µg
Product Specifications
Background
The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Overview
Purified recombinant protein of Homo sapiens leucine-rich repeat containing G protein-coupled receptor 5 (LGR5), residues 447-561aa, with C-terminal Fc tag, expressed in HEK293 cells.
Synonyms
FEX; GPR49; GPR67; GRP49; HG38
Gene ID
8549
UniProt
O75473, A0A0A8K8C7
Accession Number mRNA
NM_003667
Chromosomal Location
12q21.1
Expression System
HEK293
Tag
C-Fc
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
PBS, pH7.4, 10% glycerol
Function
Druggable Genome, GPCR, Transmembrane
Molecular Weight
38 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LGR5
Species
Human
Protein ID
NP_003658
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8549
Uniprot URL
https://www.uniprot.org/uniprot/O75473
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003667
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003658
Price
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