CD47 (NM_001777) Human Recombinant Protein
Selected Variant
PH32894M4
Size: 20 µg
Product Specifications
Background
This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]
Overview
Purified recombinant protein of Homo sapiens CD47 molecule (CD47), residues 19-141aa, with C-terminal Fc tag, expressed in HEK293 cells.
Synonyms
IAP; MER6; OA3
Gene ID
961
UniProt
Q08722
Accession Number mRNA
NM_001777
Chromosomal Location
3q13.12
Expression System
HEK293
Tag
C-Fc
Related Pathways
ECM-receptor interaction
Field of Research
ECM-receptor interaction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
PBS, pH7.4, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
35.21
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CD47
Species
Human
Protein ID
NP_001768
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/961
Uniprot URL
https://www.uniprot.org/uniprot/Q08722
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001777
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001768
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