PD L2 (PDCD1LG2) (NM_025239) Human Recombinant Protein
Product Specifications
Background
Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity) .[UniProtKB/Swiss-Prot Function]
Synonyms
B7DC; bA574F11.2; Btdc; CD273; PD-L2; PDCD1L2; PDL2
Gene ID
80380
UniProt
Q9BQ51
Accession Number mRNA
NM_025239
Chromosomal Location
9p24.1
Expression System
HEK293
Tag
C-Fc
Related Pathways
Cell adhesion molecules (CAMs)
Field of Research
Cell adhesion molecules (CAMs)
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
PBS, pH7.4, 10% glycerol
Function
Transmembrane
Molecular Weight
50 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PDCD1LG2
Species
Human
Protein ID
NP_079515
Overview
Purified recombinant protein of human programmed cell death 1 ligand 2 (PDCD1LG2), extracellular domain with C-terminal Fc fusion, expressed in human cells, 20 µg
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/80380
Uniprot URL
https://www.uniprot.org/uniprot/Q9BQ51
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_025239
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_079515
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