PD L2 (PDCD1LG2) (NM_025239) Human Recombinant Protein

Product Specifications

Background

Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Purified recombinant protein of human programmed cell death 1 ligand 2 (PDCD1LG2), extracellular domain with C-terminal Fc fusion, expressed in human cells, 20 µg

Synonyms

B7DC; bA574F11.2; Btdc; CD273; PD-L2; PDCD1L2; PDL2

Gene ID

80380

UniProt

Q9BQ51

Accession Number mRNA

NM_025239

Chromosomal Location

9p24.1

Expression System

HEK293

Tag

C-Fc

Related Pathways

Cell adhesion molecules (CAMs)

Field of Research

Cell adhesion molecules (CAMs)

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

PBS, pH7.4, 10% glycerol

Function

Transmembrane

Molecular Weight

50 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.