CD34 (NM_001773) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Overview
Recombinant protein of human CD34 molecule (CD34), transcript variant 2, extracellular domain with C-terminal Fc fusion, expressed in human cells, 20 µg
Synonyms
CD34 antigen; CD34 molecule; hematopoietic progenitor cell antigen CD34; OTTHUMP00000034733; OTTHUMP00000034734
Gene ID
947
UniProt
P28906
Accession Number mRNA
NM_001773
Chromosomal Location
1q32.2
Expression System
HEK293
Tag
C-Fc
Related Pathways
Cell adhesion molecules (CAMs), Hematopoietic cell lineage
Field of Research
Cell adhesion molecules (CAMs), Hematopoietic cell lineage
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
PBS, pH7.4, 10% glycerol
Function
Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Transmembrane
Molecular Weight
52 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CD34
Species
Human
Protein ID
NP_001764
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/947
Uniprot URL
https://www.uniprot.org/uniprot/P28906
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001773
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001764
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