CD28 (NM_006139) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]
Overview
Purified recombinant protein of Human CD28 molecule (CD28), with C-terminal Fc tag, expressed in human cells
Synonyms
Tp44
Gene ID
940
UniProt
P10747
Accession Number mRNA
NM_006139
Chromosomal Location
2q33.2
Expression System
HEK293
Tag
C-Fc
Related Pathways
Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, T cell receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis
Field of Research
Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, T cell receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
PBS, pH7.4, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
40 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CD28
Species
Human
Protein ID
NP_006130
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/940
Uniprot URL
https://www.uniprot.org/uniprot/P10747
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006139
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006130
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