CD252 (TNFSF4) (NM_003326) Human Recombinant Protein
Product Specifications
Background
This gene encodes a cytokine of the tumor necrosis factor (TNF) ligand family. The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells. Polymorphisms in this gene have been associated with Sjogren's syndrome and systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Overview
Purified recombinant protein of human tumor necrosis factor (ligand) superfamily, member 4 (TNFSF4), with C-terminal Fc tag, expressed in human cells, 20 µg
Synonyms
CD134L; CD252; GP34; OX-40L; OX4OL; TNLG2B; TXGP1
Gene ID
7292
UniProt
P23510, A0A024R937
Accession Number mRNA
NM_003326
Chromosomal Location
1q25.1
Expression System
HEK293
Tag
C-Fc
Related Pathways
Cytokine-cytokine receptor interaction
Field of Research
Cytokine-cytokine receptor interaction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
PBS, pH7.4, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
42 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TNFSF4
Species
Human
Protein ID
NP_003317
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7292
Uniprot URL
https://www.uniprot.org/uniprot/P23510
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003326
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003317
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