RAD52 (NM_134424) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014]
Synonyms
RP11-359B12.2
Gene ID
5893
UniProt
P43351, Q5DR82
Accession Number mRNA
NM_134424
Chromosomal Location
12p13.33
Expression System
HEK293
Tag
C-Myc/DDK
Related Pathways
Homologous recombination
Field of Research
Homologous recombination
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
46 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RAD52
Species
Human
Protein ID
NP_602296
Overview
Purified recombinant protein of Human chromosome 15 open reading frame 23 (C15orf23), transcript variant 3, mutant (S24F), expressed in HEK293 cells, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5893
Uniprot URL
https://www.uniprot.org/uniprot/P43351
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_134424
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_602296
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items