PLA2G12A (NM_030821) Human Recombinant Protein
Product Specifications
Background
Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]) .[supplied by OMIM, Mar 2008]
Overview
Purified recombinant protein of Human phospholipase A2, group XIIA (PLA2G12A), with C-terminal His tag, secretory expressed in HEK293 cells, 50ug
Synonyms
GXII; PLA2G12; ROSSY
Gene ID
81579
UniProt
Q9BZM1, Q542Y6
Accession Number mRNA
NM_030821
Chromosomal Location
4q25
Expression System
HEK293
Tag
C-His
Related Pathways
Alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway
Field of Research
Alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
PBS, pH7.4, 10% glycerol
Function
Druggable Genome, Secreted Protein
Molecular Weight
20 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PLA2G12A
Species
Human
Protein ID
NP_110448
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/81579
Uniprot URL
https://www.uniprot.org/uniprot/Q9BZM1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_030821
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_110448
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
TL303038V 500 µL Each
NANS Human shRNA Lentiviral Particle (Locus ID 54187)
Sign In for Pricing
View Details