Collagen X (COL10A1) (NM_000493) Human Recombinant Protein

Product Specifications

Background

This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD) . [provided by RefSeq, Jul 2008]

Overview

Purified recombinant protein of Human collagen, type X, alpha 1 (COL10A1), with C-terminal His tag, secretory expressed in HEK293 cells, 50ug

Synonyms

Collagen, type X, alpha 1; collagen X, alpha-1 polypeptide; OTTHUMP00000017049; OTTHUMP00000040411; Schmid metaphyseal chondrodysplasia; type X collagen alpha 1

Gene ID

1300

UniProt

Q03692

Accession Number mRNA

NM_000493

Chromosomal Location

6q22.1

Expression System

HEK293

Tag

C-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

PBS, pH7.4, 10% glycerol

Function

Druggable Genome

Molecular Weight

65.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.