Eph receptor A2 (EPHA2) (NM_004431) Human Recombinant Protein
Product Specifications
Background
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010]
Synonyms
ARCC2; CTPA; CTPP1; CTRCT6; ECK
Gene ID
1969
UniProt
P29317, A0A024QZA8
Accession Number mRNA
NM_004431
Chromosomal Location
1p36.13
Expression System
Sf9
Tag
C-DDK
Related Pathways
Axon guidance
Field of Research
Axon guidance
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase, Transmembrane
Molecular Weight
56.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EPHA2
Species
Human
Protein ID
NP_004422
Overview
Recombinant protein of human EPH receptor A2 (EPHA2), residues 24-537aa, with C-terminal DDK tag, expressed in sf9, 20ug
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1969
Uniprot URL
https://www.uniprot.org/uniprot/P29317
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004431
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004422
Curated Selection
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