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Eph receptor A2 (EPHA2) (NM_004431) Human Recombinant Protein

Product Specifications

Background

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010]

Overview

Recombinant protein of human EPH receptor A2 (EPHA2), residues 24-537aa, with C-terminal DDK tag, expressed in sf9, 20ug

Synonyms

ARCC2; CTPA; CTPP1; CTRCT6; ECK

Gene ID

1969

UniProt

P29317, A0A024QZA8

Accession Number mRNA

NM_004431

Chromosomal Location

1p36.13

Expression System

Sf9

Tag

C-DDK

Related Pathways

Axon guidance

Field of Research

Axon guidance

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase, Transmembrane

Molecular Weight

56.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EPHA2

Species

Human

Protein ID

NP_004422

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/1969

Uniprot URL

https://www.uniprot.org/uniprot/P29317

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004431

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004422

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