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Eph receptor A3 (EPHA3) (NM_005233) Human Recombinant Protein

Product Specifications

Background

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]

Synonyms

EK4; ETK; ETK1; HEK; HEK4; TYRO4

Gene ID

2042

UniProt

P29320, A0A140VJJ0, Q6P4R6

Accession Number mRNA

NM_005233

Chromosomal Location

3p11.1

Expression System

Sf9

Tag

C-DDK

Related Pathways

Axon guidance

Field of Research

Axon guidance

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase, Secreted Protein, Transmembrane

Molecular Weight

58.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

EPHA3

Species

Human

Protein ID

NP_005224

Overview

Recombinant protein of human EPH receptor A3 (EPHA3), transcript variant 1, residues 21-541aa, with C-terminal DDK tag, expressed in sf9, 20ug

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2042

Uniprot URL

https://www.uniprot.org/uniprot/P29320

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005233

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005224

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