Insulin Receptor R (INSRR) (NM_014215) Human Recombinant Protein

Product Specifications

Background

Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human insulin receptor-related receptor (INSRR), residues 747-921aa, with C-terminal DDK tag, expressed in sf9, 20ug

Synonyms

IRR

Gene ID

3645

UniProt

P14616

Accession Number mRNA

NM_014215

Chromosomal Location

1q23.1

Expression System

Sf9

Tag

C-DDK

Related Pathways

Prostate cancer, Regulation of actin cytoskeleton

Field of Research

Prostate cancer, Regulation of actin cytoskeleton

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase, Transmembrane

Molecular Weight

19.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.