CPLX2 (NM_006650) Human Recombinant Protein

Product Specifications

Background

Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human human complexin 2 (CPLX2), transcript variant 1, full length, with C-terminal DDK tag, expressed in sf9 cells

Synonyms

921-L; CPX-2; CPX2; Hfb1

Gene ID

10814

UniProt

Q6PUV4

Accession Number mRNA

NM_006650

Chromosomal Location

5q35.2

Expression System

Sf9

Tag

C-DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

15.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.