What is the catalog number for LYRIC (MTDH) (NM_178812) Human Recombinant Protein?

The catalog number for LYRIC (MTDH) (NM_178812) Human Recombinant Protein is PH32655I1.

What sizes are available for LYRIC (MTDH) (NM_178812) Human Recombinant Protein?

LYRIC (MTDH) (NM_178812) Human Recombinant Protein is available in the following size(s): 20 µg.

Is LYRIC (MTDH) (NM_178812) Human Recombinant Protein in stock?

LYRIC (MTDH) (NM_178812) Human Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

LYRIC (MTDH) (NM_178812) Human Recombinant Protein

Product Specifications

Background

Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human metadherin (MTDH), residues 70-582aa, with N-terminal His tag, expressed in sf9 cells

Synonyms

3D3; AEG-1; AEG1; LYRIC; LYRIC/3D3

Gene ID

92140

UniProt

Q86UE4, A0A024R9D2

Accession Number mRNA

NM_178812

Chromosomal Location

8q22.1

Expression System

Sf9

Tag

N-His

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

56.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.